Thalamus Biosciences Lucas Thal, PhD

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Services

Every engagement is a written proposal with a named deliverable, a date and a fixed fee. Imaging and cell-based work comes first; the therapeutics offers are grouped by the decision you need to make.

Imaging and cell-based science

For anyone who generates image or cell data: drug developers, CROs, imaging and instrument vendors, academic cores and tool companies. This is my core work.

Imaging and Functional Readout Audit

One assay or pipeline scored end to end, from fluorophore panel to statistics, with a prioritized fix list you can act on in a week.

From $8,000 1–2 weeks

Imaging Pipeline and Analysis Build

I design and hand over a rerunnable segmentation, feature-extraction and multivariate analysis pipeline for one assay, with the methods section already written.

From $8,000 3–5 weeks

Assay and Platform Advisory

Assay validation design, application notes, and the scientific credibility your customers ask you for — written by someone who has bought your product from the sponsor side.

Custom quote Hours to weeks, scoped with you

Therapeutics programs

Discovery biology for therapeutics in any modality — antibody, siRNA and ASO, small molecule.

What to build

Assay Cascade Design Sprint

A written cascade from biochemical to translational, with go/no-go criteria at every tier and a build-versus-outsource call per assay.

From $12,000 2–3 weeks

iPSC Disease Model Build Advisory

The lineage and source decision, the culture format, the readouts, and the QC gates that separate disease from differentiation noise.

From $15,000 4–8 weeks, two phases

PD Biomarker and Target-Engagement Plan

A biomarker hypothesis map from proximal target engagement to pathway PD to disease biomarker, with the assays, the matrices and the validation plan behind it.

From $12,000 2–3 weeks

Whether the data holds

Scientific Diligence Memo

A bench-level read of a data package — what it does and does not support, where replication risk sits, and the management questions whose answers would change the conclusion.

From $10,000 5–10 business days

Who runs it and how

CRO Selection and Study Oversight

I write the RFP, score the vendors, and then sit on your side of the weekly call until the data arrives clean.

Selection from $6,000 Selection 2 weeks; oversight monthly per study

Fractional Lead Biologist

Standing ownership of in vitro strategy — team meetings, CRO management, data review, and the science on the board slide.

From $9,500 a month 3-month minimum, 30 days' notice after that

Book an intro call Four quick questions and your contact details, then pick a time. A first conversation about your data, no pitch.